Sequencing circulating tumor cell-free DNA (cfDNA) in cerebrospinal fluid (CSF) improved diagnosis, decision-making, and clinical care in pediatric and adolescent and young adult (AYA) patients with ...

This Collection welcomes studies of the dynamics of cerebrospinal fluid and cerebral circulation in health and disease. In addition to protecting the brain, and spinal cord, from impact and injury, ...

Cerebrospinal fluid (CSF) is a type of clear liquid that surrounds, protects, and cushions your brain and spinal cord from possible injuries. The fluid is held in place by the dura mater, a dense ...

CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

A technology that diagnoses various diseases, including Alzheimer’s and Parkinson’s, using just a few drops of blood from a finger prick is called “blood biomarker measurement.” In recent years, ...

A CSF leak occurs when cerebrospinal fluid (CSF) escapes from the protective layer surrounding the brain and spinal cord. This is a serious condition that can cause headaches, seizures, or meningitis.

More than 20 y ago, we developed an animal model for chronic and continuous collection of cerebrospinal fluid (CSF) from conscious rhesus macaques. Since our previous publication in 2003, we have ...

For a human, one of the first signs someone is getting old is the inability to remember little things; maybe they misplace their keys, or get lost on an oft-taken route. For a laboratory mouse, it’s ...