T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

Leydig cells are specialised interstitial cells within the testis responsible for the synthesis of testosterone, a critical hormone for male reproductive function and secondary sexual characteristics.

The development of an embryo is one of the most fundamental processes in biology. Early in this process, it is determined ...

Cell division during the early stage of embryo development is a trade-off between speed and accuracy; the cells need to ...

Researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have uncovered a surprising link between low brain sugar levels and the development of myelin - the ...

Their findings, recently reported in the journal Nature, overturn longstanding assumptions in developmental biology and could change the way scientists think about treatments for a variety of ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic ...

This is a useful study that seeks to elucidate the molecular mechanisms underlying spinal motor circuit assembly. The authors demonstrate that loss of Onecut transcription factors in spinal motor ...

For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human immune cell—known as helper T cells—from stem cells in a ...