Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Phospholipase C (PLC) enzymes constitute a pivotal hub in cellular signalling by hydrolysing the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP₂) to generate the second messengers ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a ...

Cell walls are a crucial structure of plant life, protecting cells from damage, giving plants shape, and containing energy-rich nutrients. And yet the process of how the walls begin to form remains ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...

Peptide-based signaling systems continue to occupy a central role in modern biochemical inquiry, particularly in areas concerned with extracellular matrix (ECM) dynamics and structural protein ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...