Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Researchers discover that the GPR3 receptor acts as an immediate-early gene to jumpstart neuron and synapse development.

Phospholipase C (PLC) enzymes constitute a pivotal hub in cellular signalling by hydrolysing the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP₂) to generate the second messengers ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a ...

Cell walls are a crucial structure of plant life, protecting cells from damage, giving plants shape, and containing energy-rich nutrients. And yet the process of how the walls begin to form remains ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...

Peptide-based signaling systems continue to occupy a central role in modern biochemical inquiry, particularly in areas concerned with extracellular matrix (ECM) dynamics and structural protein ...