Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...

Novel Model Integrating TME Composition with TLS Gene Signatures Predicts Meaningful Survival Differences in Checkpoint Inhibitor-Treated Patients Cellworks Group Inc., a leader in Personalized ...

Immunotherapy for high grade CNS tumors including adult glioblastoma, anaplastic astrocytoma, pediatric high-grade gliomas, ependymoma and medulloblastoma ...

The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...

Lipid droplets (LDs) are now recognized as dynamic organelles that regulate diverse cellular processes, including membrane biosynthesis, stress ...

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as ...

Within tissues, cells are embedded in complex, three-dimensional structures known as the extracellular matrix. Their biomechanical interactions play a crucial role in numerous biological processes.

A schematic overview illustrating how the immune microenvironment is involved in diseases across various systems, including respiratory, cardiovascular, and digestive systems. Targeting cellular ...

Stem cells in most organisms typically take cues from adjacent cells. But new research from the Stowers Institute for Medical Research reveals planarian stem cells ignore their nearest neighbors and ...