编者按:2025年以来,siRNA疗法在治疗凝血相关疾病的研究方面取得了重要里程碑进展。RNA干扰(RNAi)机制通过在肝脏细胞中沉默编码凝血因子或天然抗凝物的mRNA,为治疗凝血相关疾病提供了一种全新的治疗模式。基于GalNAc偶联的递送技术,是将 ...
Superwarfarins represent a class of long‐acting anticoagulant rodenticides that exert their effect through profound inhibition of vitamin K recycling, primarily by targeting vitamin K epoxide ...
Research led by Randal J. Kaufman, Ph.D., has found that misfolded proteins in liver cells contribute to the development of liver cancer, shedding new light on the mysterious origins of one of the ...
Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite ...
For men with hemophilia B, receipt of gene therapy comprising an infusion of etranacogene dezaparvovec results in sustained endogenous factor IX expression and low annualized bleeding rates over five ...
To help diagnose von Willebrand disease or other bleeding disorders, a doctor will request various blood tests. These tests will measure the presence and activity of certain substances in the blood.
Add Yahoo as a preferred source to see more of our stories on Google. Blood clot made of red blood cells, platelets and fibrin protein strands. Thrombus, 3D illustration (Getty Images/iStockphoto) A ...
A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose ...
(Reuters) - The U.S. Food and Drug Administration said on Monday it has approved Novo Nordisk's drug Tretten to prevent bleeding in patients with a rare blood clotting disorder. Patients with ...
A potentially fatal disorder which causes blood clotting has been linked to a common cold, according to researchers from the University of North Carolina School of Medicine. The team found a ...