Bioinformaticians have now developed a unique method with which all metabolites in a sample can be taken into account, thus considerably increasing the knowledge gained from examining such molecules.

(Jena, Germany) Everything that lives has metabolites, produces metabolites and consumes metabolites. These molecules arise as intermediate and end products from chemical processes in an organism's ...

Potential pharmaceuticals are typically screened for toxicity with high-throughput assays that utilize cultured cell lines and simple endpoints like cell death or inhibition of cell proliferation.

A new non-addictive class of compounds developed by researchers at Purdue’s College of Pharmacy could lead to the treatment of chronic pain conditions, such as back pain and arthritis, in the absence ...

Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant (MDR) Gram-negative bacteria. The new compounds target a protein, LpxH, ...