In the annals of napkin illustration, continuous drug tablet manufacturing may have only one entry: Fernando Muzzio’s 2003 depiction of a tableting line for Janet Woodcock, then head of the US Food ...

Biopharma 4.0 is often presented as an all-or-nothing proposition, when in fact its components have all been around for a while and have independent value. It appears the major challenge will be ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

In the manufacture of biotherapeutic drugs, the goal is to maximize production while minimizing costs, even though achieving this goal may involve a difficult transition—specifically, a transition ...

A photo of technicians working in front of a process train. Novartis's continuous manufacturing center in Basel, Switzerland, replicates an end-to-end manufacturing process developed at the ...

Historically, pharmaceutical products have been produced in a traditional ‘batch’ system, in which every operation is executed separately using a defined quantity of materials. In batch manufacturing ...