Less than 2% of the genome codes for proteins; the rest, once called 'junk DNA', contains regulatory elements. Researchers ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

New findings show that the genome’s 3D structure is constantly changing, with NIPBL guiding loop formation that regulates active genes. Faulty folding dynamics may underlie cancers and developmental ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can control gene activity even after losing one of their major gene-regulatory ...

In a giant feat of genetic engineering, scientists have created bacteria that make proteins in a radically different way than all natural species do. By Carl Zimmer At the heart of all life is a code.

Researchers have uncovered how a key DNA repair enzyme is recruited and activated inside cells, answering long-standing questions about how cells protect and repair their DNA and providing the ...