非洲猪瘟是由ASFV引起的猪烈性传染病，具有高致死率，自2018年传入我国以来，已造成巨大经济损失，严重威胁全球养猪业安全。由于ASFV基因组庞大复杂，编码蛋白众多，且缺乏有效抗病毒药物和商业化疫苗，其防控一直是全球兽医领域的重大难题。病毒DNA聚合酶作为基因组复制的核心“引擎”，是抗病毒药物开发的关键靶点，但ASFV的DNA聚合酶的复制机制此前尚未被完全解析。

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

A new study has illuminated an important process that occurs during cell division and is a likely source of DNA damage under some circumstances, including cancer. A new study from scientists at the ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...