当单细胞图谱遇上序列到功能模型，我们是否正在接近一个更具体的问题：非编码DNA如何在不同细胞、不同疾病状态中写出不同的表达程序？ 5月25日，《Nature Methods》的研究报道“Decoding sequence determinants ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

A research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a method to accurately and efficiently read DNA containing non-standard bases — a task once thought too ...

Transcriptomic Predictors of Survival for Palbociclib + Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor–Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial Our findings revealed a ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

A new DNA sequencing technique that delivers faster and more accurate bacterial infection diagnoses could be implemented nationwide. The method, developed by the Medicines and Healthcare products ...