Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the roundworm's ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

SAN DIEGO--(BUSINESS WIRE)--TriLink BioTechnologies and Alphazyme, both part of Maravai LifeSciences, have collaborated to launch CleanScribe™ RNA Polymerase, a novel enzyme that reduces ...

MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

Building on its success against COVID-19, mRNA technology holds promise for novel vaccines and treatments targeting various diseases. However, a critical challenge remains: current in vitro ...

Adenosine deaminase acting on RNA (ADAR) is the enzyme responsible for adenosine-to-inosine (A-to-I) RNA editing, a process ...

Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...

When scientists sliced into a block of Siberian permafrost and pulled out a woolly mammoth nicknamed Yuka, they expected to ...