Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...

Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize ...

Week 3 of pregnancy is a critical stage when the embryo begins to grow rapidly. During this week, cells divide at an astonishing rate, laying the foundation for all future tissues and organs. This ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

When Berna Sozen, PhD, assistant professor of Developmental Stem Cell Biology at Yale, was in her first weeks of pregnancy, she couldn’t help but wonder about what exactly was going on in the “black ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

New findings offer insight into why some embryos fail to develop past zygotic genome activation (ZGA), pointing to an unexpected root of human infertility. A critical point in early development is ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...

Why doesn’t a ‘good’ embryo always lead to pregnancy in IVF? Explore key factors beyond embryo quality that affect IVF ...

Rowan University biology professor Natasha Shylo is exploring left-right asymmetry development with a grant from the National Institutes of Health.