Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St.

Find how Circularization for High-throughput Analysis of Nuclease Genome-wide Effects by Sequencing Base Editors ...

Existing gene-editing technologies have led to significant advances in both medicine and food production. However, momentum appears to be slowing, particularly in health applications, as early hype is ...

Delivering genome editing machinery into plant cells remains a challenge despite the dire need for high yield crops with enhanced nutritional value that are resistant to disease and resilient in the ...

Like the human immune system, bacteria learn from past infections. CRISPR sequences—short snippets of DNA from previous viruses—guide destructive enzymes towards invading bacteriophages that express ...

Genome editing is no longer a futuristic concept — scientists are already rewriting the genetic material of living organisms to cure diseases, enhance crops, and revolutionize biotechnology. This ...

However, how these regions corresponded to specific sequences of DNA remained elusive. Plant scientists suspected that understanding this mechanism could help identify targets during disease ...

However, traditional gene delivery methods, such as Agrobacterium-mediated transformation and gene guns, are often slow, inefficient, and can damage plant tissues. These highlight the need for more ...