Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...

Under his microscope, Jun Wu could see several tiny spheres, each less than 1 millimetre wide. They looked just like human embryos: a dark cluster of cells surrounded by a cavity, and then another ...

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The most advanced lab-made human embryo models look like the real thing — they resemble, though don't perfectly replicate, natural embryos about 14 days into development. These lab-made embryo models ...

Some newly reported clumps of cells growing in lab dishes have been hailed as the closest things to human embryos that scientists have ever made in the lab. These entities are human embryo models — ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...