The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...

A modified pig liver transplanted into a human patient appears to have functioned normally for the duration of the investigation with no signs of rejection. For 10 days, the liver performed its basic ...

The majority of human illnesses is caused by damage of a single organ like the liver whose failure accounts for 2M deaths worldwide every year. Orthotopic transplants are the only curative therapy ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

A pig's liver has been transplanted into a human recipient for the first time in a ‘milestone’ for organ transfers between animals and people. Scientists in China used a liver taken from a seven-month ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

Doctors in China claim they successfully transplanted a pig’s liver into a living human patient in a b-oink-ing mad medical first. They also reckon that it actually worked for over a month before ...

A team of researchers led by bioengineer Shaochen Chen will use 3D printing techniques to shape stem cells produced by local firm Allele Biotechnology ...

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient. The ...

New MIT research is revealing how long-term high-fat diets may prime liver cells for cancer by forcing them into survival mode over extended time periods.