Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother. This mechanism to temporarily slow ...

The majority of fertilized eggs die and are resorbed into the body. ZEISS Microscopy/Flickr, CC BY-SA As an evolutionary biologist whose career has focused on how embryos develop in a wide variety of ...

The schematic outlines the development and validation of an AI model for evaluating in vitro-fertilized human embryos. It utilizes images captured at specific time points post-insemination (Day 1 and ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...

Researchers have discovered a potential 'pause button' in the earliest stages of human development. Whether humans can control the timing of their development has long been debated. The new study ...

At some point in our evolution, we lost the ability to activate a reproductive mechanism called embryonic diapause, which slows development, usually during the blastocyst stage. And so, unlike mammals ...

Only about one out of three conceptions leads to birth. 1 Approximately a third of embryos fail to attach to the uterus, while another third is lost after the embryo implants. “Human reproduction is ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...

Our ancient past isn't always buried history. When it comes to our DNA, nearly 9% of the human genome is made up of leftover genetic material from ancient viruses (called endogenous retroviruses or ...