Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

Uncovering mechanisms regulating immune system responses is key to strengthening and redirecting them whenever necessary in cancer and infections as well as understanding autoimmune diseases. However, ...

This study focused on how NMDAR, an important cell surface receptor, triggers a complex chemical cascade in postsynaptic neurons in the nucleus accumbens region of the brain. More specifically, the ...