Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured ...

Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.

This study is reported by Jia-Tang Li’s group from the Chengdu Institute of Biology, Chinese Academy of Sciences. The development of limbs is significant for the origin and evolution of tetrapods, ...

Split hand/foot malformation (SHFM) is a congenital limb anomaly distinguished by the absence or malformation of the central digits in the hands and feet, often accompanied by syndactyly or ...

To shed light on the principles that govern tissue dynamics across species, RIKEN biologists have developed a new method for analyzing the development of vertebrate limbs. These principles could help ...

Scientists have created a spatial atlas of the incredible process of human limb development, including steps that show digits emerging from a bud as cells recede, instead of growing outward. With ...

Globally, close to 60 million people are living with limb loss. Amputations can result from various medical conditions such as tumors, infections, and birth defects, or due to trauma from industrial ...

Fingerprints are among the most distinctive features of human biology, serving as enduring identifiers for individuals and as windows into genetic and developmental processes. The three major ...

Fins and limbs and fins into limbs : the historical context, 1840-1940 / Peter J. Bowler -- Skeletal changes in the transition from fins to limbs / Michael I. Coates and Marcello Ruta -- A historical ...