Matrix metalloproteinase 1 (MMP-1) is necessary for degradation of interstitial collagen types I, II, and III, which are the major constituents of the extracellular matrix (ECM). Increased expression ...

MONTREAL — Mycophenolate mofetil can be substituted for cyclophosphamide for the immunosuppressive treatment of scleroderma-related interstitial lung disease, and might even be safer, according to ...

"I like to say you have good days, bad days, and perhaps worse days." That's how Harold Abney describes Scleroderma - a disease he's lived with for 19 years. "It's a day by day conquest," he says.

Suggested Citation: "4 Scleroderma." National Academies of Sciences, Engineering, and Medicine. 2022. Selected Immune Disorders and Disability. Washington, DC: The National Academies Press. doi: ...

Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...

Please provide your email address to receive an email when new articles are posted on . DESTIN, Fla. — There is a close temporal link between cancer and the onset of scleroderma in patients with ...

AUSTIN — A group of researchers at the Hormel Institute in Austin recently published a scientific paper detailing a significant discovery in a group of diseases known as scleroderma. "Centromere ...

Limited scleroderma is a chronic autoimmune disease characterized by hardening of the hand’s skin and vasculature. The disease is rare—only about 77,000 Americans have it—and it afflicts women three ...

Cheryl Argiros has scleroderma, a rare and often fatal skin-hardening disease that defies treatment. Her facial skin is like polished stone. Cheryl Argiros of Coventry, Conn., already has participated ...