Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide. In most cases, this condition occurs as a result of an ...

When developing drugs, we rely on animal models to test drugs in an entire system before first-in-human studies. However, animals aren’t human and interspecies differences in pharmacology, physiology, ...

Suggested Citation: "6 Assessing Safety and Toxicology." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in Support of Precision ...

AlCl 3: Aluminium chloride; Apo-E: Apolipoprotein E; Aβ-40: amyloid β-40; Bax: Bcl-2-associated X protein; G-CSF: granulocyte-colony stimulating factor; IL-1β ...

Behavioral analysis can provide a lot of information about the health status or motivations of a living being. A new technology developed at EPFL makes it possible for a single deep learning model to ...

Torie Bosch is the First Opinion editor at STAT. First Opinion is STAT’s platform for interesting, illuminating, and provocative articles about the life sciences writ large, written by biotech ...