An interactive toolbox for standardizing, validating, simulating, reducing, and exploring detailed biophysical models that can be used to reveal how morpho-electric properties map to dendritic and ...

When triggered by an odor, rapid changes in membrane voltage and intracellular calcium ion levels occur in nematode olfactory neurons, causing membrane voltage sensors and calcium ion sensors to ...

BOSTON, Mass. (July 15, 2024)—A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children’s Hospital has revealed that an immune protein impacts neuronal protein synthesis in ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew.

The innate immune protein C1q seems to have a thing for neurons. Already implicated in synaptic pruning by microglia, now it is reported to also slow down protein production in neurons of the aging ...