Non-inferiority trials are a valuable type of clinical trial to evaluate new treatments that might have differing benefits. Such trials are increasingly used, but have methodological challenges in ...
The Galleri-Medicare study called REACH (Real-world Evidence to Advance Multi-Cancer Early Detection Health Equity) is a non-randomized, observational study of 50,000 Medicare beneficiaries. The ...
Antibiotic management of acute uncomplicated appendicitis among children was inferior to appendectomy, a randomized non-inferiority trial showed. For nearly 850 children with available primary outcome ...