Many people around the world either consume omeprazole or lansoprazole for their digestive problems or gut issues.However, ...

A recent randomised controlled trial showed that proton pump inhibitors (PPIs), compared with histamine-2 receptor antagonists (H2RAs), induce greater gut microbiome alterations and oral-to-gut ...

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the ...

Proton pump inhibitors (PPIs), widely prescribed for acid-related disorders like GERD and peptic ulcers, are associated with significant adverse effects when used long-term. This review highlights ...

While 50%-80% of PPI prescriptions are unjustified, particularly for unnecessary nonsteroidal anti-inflammatory drug (NSAID)-related ulcer prophylaxis, PPIs remain underprescribed for patients at risk ...