撰文丨王聪编辑丨王多鱼排版丨水成文对于成百上千万患有神经痛的人来说,哪怕是最轻微的触碰也会让他们难以忍受。长期以来,科学家们一直怀疑,受损的神经元之所以功能衰退,是因为这些细胞中的能量工厂——线粒体,无法正常运作。而现在,一项发表于 Nature ...
该研究首次揭示了外周神经系统中胶质细胞向神经元转运线粒体的保护性机制,为理解糖尿病和化疗相关外周神经病变提供了新的代谢视角,也为开发靶向胶质—神经元能量互作的治疗策略奠定了基础。
文章中,研究人员通过扫描电镜与透射电镜观察,首次在小鼠和人类的背根神经节中发现了卫星胶质细胞与感觉神经元之间隧道纳米管样的超微结构。这些纳米管就像细胞间搭建的“微小高速公路”,允许线粒体直接输送。进一步研究发现,一种名为MYO10的肌球蛋白在这一过程中扮演关键角色—它负责驱动纳米管的形成,是线粒体“快递”能否顺利发货的“调度员”。
Danish national registry data suggest adults with type 2 diabetes taking SGLT2 inhibitors have a slightly lower risk of developing diabetic foot problems than those taking GLP-1 receptor agonists.
Patients receiving chemotherapy-induced peripheral neuropathy experience persistent, clinically significant symptoms months after treatment.
Add Yahoo as a preferred source to see more of our stories on Google. Your nervous system is a key force behind so many important bodily functions. But when your peripheral nerves—those found outside ...
Diabetic neuropathy is a common, progressive complication of diabetes characterized by nerve damage that leads to chronic ...
Please provide your email address to receive an email when new articles are posted on . Diabetic peripheral neuropathy is associated with a decline in cognition for people with type 2 diabetes, ...
These data indicate that Black race is an independent risk factor for the development of BIPN. Additional prevention strategies, close monitoring, and appropriate supportive care measures are ...
Hispanic people have an increased risk of peripheral neuropathy compared to white people that cannot be explained by many health, lifestyle and social risk factors, according to a study published July ...