Thrombocytopenia, inherited as a dominant trait, was present in three generations of a kindred. The clinical picture was quite similar to that of idiopathic thrombocytopenic purpura, but ...

Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke, researchers have demonstrated -- for the first time -- through a combination of both ...

Study of the bleeding tendency in uremia in 26 subjects, 10 of whom were bleeding, showed platelet counts and plasma coagulation factors to be normal. There was a significant inverse correlation ...

The coronavirus disease-19 (COVID-19) pandemic that emerged in Wuhan, China, in late December 2019 spread rapidly throughout the world and has caused over 6.5 million deaths. The disease is caused by ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

As we age, our immune system quietly loses its edge, and scientists have uncovered a surprising reason why. A protein called ...