Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found that a key ...

An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers. The scientists identified a potential central mechanism by which cancer ...

Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...

Dewpoint has selected a novel small molecule to prevent the formation of abnormal TDP-43 protein clumps in ALS and other ...

Protein arginylation is an evolutionarily conserved post‐translational modification whereby arginine is covalently attached to specific residues on target proteins. Mediated principally by the enzyme ...

A study suggests overactive VCP may contribute to ALS nerve damage by disrupting nuclear pore proteins in genetic ALS.

Researchers have developed technologies that allow damaged proteins to be shredded or healthy ones installed. This may ...

Many people still don’t understand how protein works, why it matters or the best ways to get enough of it in their diet. Here ...