"By following universal paralogs," says Kaçar, "we can connect the earliest steps of life on Earth to the tools of modern ...

Genetic studies now identify millions of variants across human populations, yet most disease-associated signals fall outside protein-coding regions. This ...

Deep sequencing has revealed thousands of eukaryotic protein-coding genes that defy the central dogma, producing circular noncoding RNAs rather than linear messenger RNAs. For some genes, the ...

Telomeres are repetitive sequences of DNA that can be found at the ends of chromosomes, where they form a kind of protective cap. Telomeres get shorter every time a cell divides, and they are thought ...

There are billions of nucleotides in the human genome, and researchers once thought that there could be as many as 100,000 protein-coding genes encoded within the human genome. One of the main goals ...

A new review by Erich Bornberg-Bauer and Lars A. Eicholt summarizes current understanding of protein-coding de novo genes—genes that originate from previously non-coding DNA. Once considered rare or ...

MIT’s AI system boosts precision protein drug production, cutting development costs by learning the “language” of genetic sequences.