Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

The Expi293™ PRO Expression System is a high-performance transient HEK293 mammalian protein expression platform designed to help researchers express more proteins faster, at higher yields, and with ...

A comprehensive assessment of protein expression product and service providers, along with information on several relevant parameters, such as year of establishment, company size and location of ...

This article and associated images are based on a poster originally authored by Marina Fedorova and Ian Hiles and presented at ELRIG Drug Discovery 2024 in affiliation with GSK. This poster is being ...

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, hemophilia and, recently, Huntington's disease, a fatal neurological ...

The latest short science news items from C&EN. Proteins are vital for life, involved in virtually every biochemical process that makes life possible. They comprise one or more amino acid chains ...

Stay up to date on the latest science with Brush Up Summaries. Finally, although transgenic animals and mammalian cell culture systems promote optimal expression due to correct protein modifications, ...

A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

Impact of lorlatinib dose modifications on adverse event outcomes in the phase 3 CROWN study. RC108 in combination with furmonertinib in patients with locally advanced or metastatic EGFR-mutated ...