Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...

Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The proteins that give plants their shape and structure are also involved in ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

John Jumper (S.M. ’12, Ph.D. ’17) was awarded the Nobel Prize in Chemistry in 2024 for his contributions to the development of AlphaFold, an AI model that revolutionized protein structure prediction.

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...

Imagine trying to design a key for a lock that is constantly changing its shape. That is the exact challenge we face in modern drug discovery when dealing with intrinsically disordered proteins.

Scientists have developed a new blood test that could spot Alzheimer’s earlier by detecting hidden changes in how proteins fold in the bloodstream.

HIV is a lifelong infection that, without proper antiviral treatment, will kill cells of the immune system and leave individuals susceptible to infections and cancers. The longevity of this virus ...

Alzheimer's disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer's Association. Current tests often measure the levels of two proteins-amyloid beta (Aβ) and ...

Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need for artificial intelligence (AI) models to effectively ...