In the cerebral cortex, extrinsic and intrinsic excitatory glutamatergic pathways terminate on principal glutamatergic neurons and local inhibitory GABAergic interneurons. Activation of these pathways ...

The mammalian brain is known to produce mental representations of the spatial environment, known as cognitive maps, that help humans and animals navigate their surroundings. A subpopulation of neurons ...

Memory dysfunction in Alzheimer's disease may be linked to impairment in how the brain replays our recent experiences while we are resting, according to a new study in mice by University College ...

Our brain’s memory center bears a sleek design. A peek into living tissue from human hippocampi, a brain region crucial for memory and learning, revealed relatively few cell-to-cell connections for ...

New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, identifying two molecules that must be present before synapses, the ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.