Two papers present novel techniques for more precisely mapping R loops — hybrid nucleic acid structures in which RNA is hybridized to one strand of DNA while the other strand of DNA is displaced and ...

R-Loops是指出现在基因组DNA中的RNA: DNA三链杂合环结构。它们是在基因组中编码和非编码区域的新生RNA转录过程中形成的。R-Loops具有重要的生物学功能，在临床上与癌症、神经和心血管疾病有重要联系。 R-loop测序技术服务 研究RNA通过形成R-LOOP调控基因表达，以 ...

R-loops, three-stranded RNA–DNA hybrids, naturally form during gene activity and DNA repair. In balance, they help regulate genes and maintain genome stability; when uncontrolled, they can damage DNA ...