The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

High background noise in RNA samples can impact read accuracy and increase sequencing costs. Optimizing sample quality enables better microRNA mapping and more reliable insights in transcriptomics and ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Suggested Citation: "1 Introduction." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for Sequencing RNA and Its Modifications: A New Era for Biology and Medicine.

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Since the advent of the Human Genome Project, scientists have expanded efforts to map complete biological datasets that encompass entire molecular families, such as DNA, RNA, proteins, and metabolites ...

In the quest for RNA biomarkers indicative of fruit maturity, a cost-effective, reliable workflow is crucial. Accurate harvest timing is critical for shelf life and apple quality, but at present, ...

Immunotherapy has been a revolutionary breakthrough for cancer therapeutics, but it is still hampered in that it only benefits certain patients. Moreover, the molecular determinants of immunotherapy ...