RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...

The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding experimental ...

RVPSD共收录154,716个RNA病毒蛋白结构，覆盖5,263种RNA病毒和149个病毒科，是目前最大的RNA病毒蛋白结构数据库。所有蛋白结构均基于AlphaFold2预测获得，其中84.9%的结构具有较高结构置信度（pLDDT＞70）。数据库在 ...

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...

A study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science ...

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

Researchers show how LGP2 binds viral RNA ends, moves along the strand, and helps MDA5 form filaments that amplify antiviral ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

New research shows that lipid nanoparticles used in mRNA vaccines may deliver RNA more effectively when their structure is ...

Neurons have a "hibernation mode." Scientists discover how brain cells use RNA tentacles to lock their protein factories ...

A strand of RNA just 45 nucleotides long has been discovered to perform two key reactions required for self-replication. The molecule, which is a kind of RNA enzyme, offers a tantalising clue towards ...

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.