Bacterial ribosomes are central to protein synthesis, and their regulation is vital for adaptation to environmental stresses. Under conditions such as nutrient deprivation, cold shock or hypoxia, ...
Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...
Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...
A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...
These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...
A team of researchers used a new technique, called high-resolution template matching, or HRTM, to uncover in unprecedented detail the movement of ribosomes -- the molecular structures that synthesize ...
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Researchers discover how aggressive breast cancer controls protein production
A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its ...
Proteins of all sizes and shapes do most of the work in living cells, and the DNA sequences in genes spell out the instructions for making those proteins. The crucial job of reading the genetic ...
During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...
This study is led by Prof. Ren Sun (Westlake University) and research fellow Yushen Du (Cancer Institute, the Second Affiliated Hospital, Zhejiang University School of Medicine). Myelotoxicity is the ...
At one time or another, most of us have played with a flipbook, using our thumbs to rapidly flip a series of pictures to create an illusion of movement. Scientists use a similar technique to study the ...
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