In 1997, Sanger, Nicklen and Coulson described a method for determining DNA nucleotide sequences. 1 Nearly five decades later, Sanger sequencing remains an entrenched technology for targeted ...

Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

Patterns of care in adjuvant systemic therapy of patients with stage III melanoma: A U.S. population-based study.

The Human Genome Project was an international scientific research project set out to map, identify, and sequence all the genes that make up the human genome, as well as improve the tools for data ...

The first DNA sequencing was performed by Sanger and co-workers in the 1970s, using a method based on the attenuation of the growing nucleotide chain with dideoxythymidine triphosphate (ddTTP). The ...

The purpose of the whole-genome sequencing module is to provide an overview of whole-genome sequencing and next-generation sequencing, including historical, technical and utilization perspectives. The ...