Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

Community-developed approach combines multi-contact 3C with HiFi sequencing to deliver haplotype-resolved assemblies from minimal input materialMENLO PARK, Calif., Jan. 08, 2026 (GLOBE NEWSWIRE) -- ...

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

A new method vastly improves on the existing approach for single-cell genetic sequencing, enabling scientists to read the genomes of individual cells and viral particles in the environment more ...

Research on gastrointestinal diseases, especially cancer, has mainly focused on epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the ...

Leveraging single-cell sequencing, this study presents the first cell-resolved molecular map of human scalp aging, revealing that the core mechanism of early senescence involves a significant ...