A collection of protocols covering a variety of methods to achieve super resolution in microscopy to include structured illumination, single-molecule fluorescence and localization-based approaches.

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Characterizing cells based on their surface proteins is a key concept in cell biology research that extends substantially into diagnostics and therapeutics. Notable examples include reporting the ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

When trying to measure molecular structures with nanometer precision, every bit of noise shows up in the data: someone walking past the microscope, tiny vibrations in the building and even the traffic ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in diseases Katarina Zimmer, Knowable Magazine Innovative techniques are helping ...

Researchers have shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical components that enable super-resolution imaging, with each lens costing less ...

Add Yahoo as a preferred source to see more of our stories on Google. Composite of three mages from new microscope technology show a cell's replication machinery in green, already-replicated DNA is ...

Current calibration methods rely on artificially constructed DNA structures or specific cellular features, each with significant drawbacks. DNA-based rulers require complex chemical synthesis and only ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...