The mode of TRPM2 channel activation by ADPR and Ca 2+ evolved through at least three identifiable stages, from a relatively simple one in TRPM2s from Cnidaria, such as the nvTRPM2, to an intermediate ...

An updated evolutionary model shows that living systems evolve in a split-and-hit-the-gas dynamic, where new lineages appear in sudden bursts rather than during a long marathon of gradual changes.

Evolutionary biologist Telford explores in this captivating debut history how the diversity of life on Earth came to be. To unravel this complex story, Telford turns to life’s evolutionary tree—the ...