Tissue microarray (TMA) technology has transformed colorectal cancer research by enabling simultaneous analysis of hundreds of tissue samples under uniform experimental conditions. In this approach, ...

Barely five years ago, Juha Kononen, then at the National Cancer Institute, presented a straightforward way of constructing tissue microarrays (TMAs): a glass slide covered with as many as 1,000 cores ...

Tissue microarrays combines tens to hundreds of paraffin-embedded tissue cores into a single paraffin block. It is a practical and highly effective technique for high-throughput analyses of various ...

In 1997, Juha Kononen, a postdoctoral fellow at the National Human Genome Research Institute, was pondering the significance of the recently developed DNA microarray. He was studying genetically ...