Although R loops can occur at different genomic locations, the factors that determine their formation and frequency remain unclear. Emerging evidence indicates that DNA breaks stimulate DNA–RNA hybrid ...

Researchers have found a new example of how the machinery that controls the transcription of DNA to messenger RNA (mRNA) is tailored to specific cells or genes. September 14, 2001 -- Researchers have ...

Researchers found that in the model organism E. coli, the fidelity of transcribing DNA comes at the expense of DNA repair. A groundbreaking and surprising discovery provides a major conceptual change ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...