脑血管网络对于维持神经元功能和保持大脑的稳态至关重要。大脑血管系统在胚胎发育早期就开始形成，起源于神经周围的血管网，并通过侵入点侵入神经管。然而，在出生时，小鼠和人类的脑血管结构仍然较为稀疏，具有原始的结构、有限的动脉静脉分化以及未成熟的星形胶质细胞和周细胞覆盖，这突显了这一阶段神经血管单元的不成熟性。

The development of cerebral organoids can offer opportunities to understand neurodevelopment and brain disease but faces several limitations, such as the lack of vasculature. In this study, ...

FesariusTherapeutics, Inc., a commercial stage bioregenerative technology company focused on the development, manufacture and commercialization of solutions for the Advanced Reconstructive Surgery and ...

(Nanowerk News) The Interdisciplinary Research Institute of Grenoble (CEA-Irig), CEA-Leti and fellow European and Canadian institutes and researchers have demonstrated the complete vascularization of ...

AIM Biotech, a Singapore- and Boston-based company, announced the launch of the organiX System—a lab tool to closely model human disease by adding vascularization and immune competence to organoids, ...

Researchers from the Paris Brain Institute and Sainte-Justine University Hospital in Montreal have, for the first time, revealed the key stages of vascular development in the brain, from birth through ...

There has been an increase in the number of people over 65 who have needed spinal fusion surgery, and many have focused on trying to create a biomimetic scaffold that induces vascularization.