撰文丨王聪编辑丨王多鱼排版丨水成文mRNA 疫苗，由纯化的经过核苷修饰的 mRNA 被脂质纳米颗粒（LNP）封装而成，mRNA 疫苗通过促进滤泡辅助性 T（Tfh）细胞分化来激发保护性抗体。而递送 mRNA 疫苗的脂质纳米颗粒（LNP）本身具有固有的佐剂活性。然而，核苷修饰的 mRNA 被感知的程度及其对 Tfh ...

美国研究人员最新分析发现，部分晚期肺癌和皮肤癌患者在接受免疫治疗前后接种新冠 mRNA 疫苗，生存时间明显长于同期未接种患者，提示新冠疫苗可能在悄然增强机体抗癌免疫反应，为“通用型癌症疫苗”概念提供了重要临床线索。这项研究由佛罗里达大学和得克萨斯大学 ...

Over the last several days, the safety and efficacy of messenger RNA, or mRNA, vaccines have come under intense scrutiny. On Tuesday, the U.S. Food and Drug Administration announced plans to limit ...

When it comes to cancer, there’s innovation both on the diagnostics and the treatment front thanks to messenger RNA, or mRNA, a genetic material we all got acquainted with during the COVID-19 era as ...

mRNA expert Jeff Coller spoke with Live Science about the future of mRNA vaccines in the United States in the aftermath of huge federal funding cuts. When you purchase through links on our site, we ...

mRNA vaccines train the immune system in a similar way to traditional vaccines, but they use a different strategy to get there. When you purchase through links on our site, we may earn an affiliate ...

SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.

为解决新生儿因免疫系统不成熟且缺乏有效疫苗而面临流感重症高风险的问题，研究人员在新生非人灵长类动物中评估了表达血凝素 (HA)的mRNA-LNP疫苗的效力。结果显示，该疫苗诱导了高水平的HA特异性抗体，包括中和及非中和功能，并显著降低了攻毒后的病毒载量和肺部病理损伤。该研究为开发保护6月龄以下婴儿的mRNA疫苗提供了关键临床前证据。

Covid vaccines turned mRNA treatments from a long-simmering research topic into a dinner table conversation. We remember the shot all too well. But these have a universal problem: Needles. Rather than ...

MRNA's stock surged 4,211% during COVID-19 but has since plummeted to $31, reflecting a significant bubble and raising concerns about its future. Declining revenue and net income, driven by reduced ...