The importance of angiogenesis for growth and viability of solid tumors has been established. Knowledge on these relations in hematological tumors, however, is circumstantial. Tumor microvessel ...

针对COVID-19重症预测缺乏特异性标志物的问题，研究人员聚焦肥大细胞（MC）激活特征，通过检测血清中类胰蛋白酶（tryptase）、羧肽酶A3（CPA3）、糜蛋白酶（chymase）和前列腺素D2（PGD2）水平，构建了多指标联合预测模型。研究发现MC激活与疾病严重程度显著相关 ...

MultiChip: A new diagnostic tool to perform gene expression analysis and CNV in one array. Background: Tryptase, a serine protease stored and released from mast cells (MCs) granules has been ...

HAMPTON, N.J., June 06, 2020 (GLOBE NEWSWIRE) -- Celldex Therapeutics, Inc. (CLDX) today announced results from the Company’s Phase 1 randomized, double-blind, placebo-controlled, dose escalation ...

Please provide your email address to receive an email when new articles are posted on . Patients with alpha tryptase had more anaphylaxis than patients who only had B-tryptase. 65% of patients with ...

Unspecific and unexplained medical complaints can be frustrating to both patients and clinicians. A cause for these complex symptoms and signs may now have been identified. Taken collectively, these ...

--Data strongly support expanding development into mast cell driven diseases----Data presented in a late-breaking session at EAACI Annual Congress 2020-- CDX-0159 demonstrated a favorable safety ...

针对卵巢纤维化在早发性卵巢功能不全(POI)中的关键作用，上海交通大学医学院附属仁济医院团队揭示了肥大细胞类胰蛋白酶 ...

Adequacy of biopsy samples for molecular testing in patients with non-small cell lung cancer. Analyses of the immunologically relevant gene transcript by qRT-PCR in primary cutaneous melanoma by the ...

A genetic explanation for a syndrome characterized by multiple frustrating and difficult-to-treat symptoms, including dizziness and lightheadedness, skin flushing and itching, gastrointestinal ...

PORTAGE, Mich.--(BUSINESS WIRE)--Thermo Fisher Scientific Inc., the world leader in serving science, today announced that its immunodiagnostics business has received 510(k) clearance of the Thermo ...