Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...

Cancer research laboratory tests can now be done using micro-physiological systems mimicking human physiology, allowing ...

The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...

T cells dynamically adapt to signals in the TME, transitioning between effector, exhausted, and regulatory states. Cellular interactions, metabolic stress, and physical barriers (e.g., ECM) shape ...

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors ...

EMBL scientists discovered self-sustaining inflammatory circuits in the bone marrow stem cell microenvironment that precede blood cancers. The illustration shows cancer cells against a background of ...

As people age, their immune function gradually declines, coinciding with increased cancer rates. However, the precise reasons behind age-related dysfunction of CD8+ T cells in cancer remain unclear.

Stopping cancer cells from entering a soft biomechanical state could help the immune system clear dormant cancer metastasis.