EMBL scientists discovered self-sustaining inflammatory circuits in the bone marrow stem cell microenvironment that precede blood cancers. The illustration shows cancer cells against a background of ...

T cells dynamically adapt to signals in the TME, transitioning between effector, exhausted, and regulatory states. Cellular interactions, metabolic stress, and physical barriers (e.g., ECM) shape ...

Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors ...

Cancer neuroimmunology integrates the study of the nervous system's influence on tumor immunity, highlighting an intricate ...

Scientists have found a way to supercharge lung cancer treatment by transplanting healthy mitochondria into tumors, which both boosts immune response and makes chemotherapy far more effective. By ...

Combination therapies represent a promising frontier in cancer treatment, addressing the critical need to enhance efficacy ...