A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Researchers identified invasive early disseminated cancer cells and immunosuppressive macrophage signaling that promote ...

Roswell Park Comprehensive Cancer Center postdoctoral researcher Catherine Rono studies how metabolic stress in myeloid cells ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Breast cancer cells (green) invading through a layer of fibroblasts (red) (photo: Luke Henry / the ICR, 2009) Cells from the most common form of breast cancer can reprogram their metabolism to help ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

The study of metabolism within the tumour microenvironment (TME) is a rapidly evolving field that holds significant implications for understanding cancer pathogenesis and developing novel therapeutic ...

A cancer drug class best known for attacking tumors may also help your immune system remember them better. Researchers at ...

They discovered a high-fat diet accelerates tumor growth and invasion. They also found it causes an increase in the enzyme ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...