A review in Glycoscience & Therapy summarizes advances in selective editing of N-glycan signals on living cell surface via the LCS‑NGS technology platform. It focuses on enzyme‑based strategies ...

Living cell surface N-glycans act as a "glycan code" that mediates cell–cell communication, immune recognition, and disease progression. Unlike ...

(a) The initially proposed antifreeze xylomannan; (b) the other three types of possible xylomannan glycans; (c) schematic illustration of the iterative exponential glycan growth (IEGG) strategy.

The addition of sugars to a protein structure may affect the stability of the protein, interactions of receptors with ligands, and signaling pathway activity. This modification, called glycosylation, ...

In response to a request from the National Institutes of Health (NIH), the Food and Drug Administration (FDA), the U.S. Department of Energy (DOE), and the National Science Foundation (NSF), the ...

Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough. The discovery ...

NEWARK, Del.--(BUSINESS WIRE)--Uvax Bio, LLC, a privately held, preclinical-stage vaccine company, today announced that the International Union of Pure and Applied Chemistry (IUPAC) has selected the ...