Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

In 2005, few neuroscientists would have bet that electron microscopy could map entire neural circuits in three dimensions. The technique was slow and cumbersome, offering only thin slices of brain ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Two labs at the University of Utah’s Department of Chemistry joined forces to improve imaging tools that may soon enable scientists to better observe signaling in functioning cells and other molecular ...

Is it possible to know exactly where to point a microscope in order to capture the precise moment a bacterium or a virus infects a cell? In order to take high resolution microscopic images of living ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Using light to measure ever-smaller objects has been central to progress in many scientific disciplines for centuries. As far back as 1873, German physicist Ernst Abbe proved that light diffraction ...

Evanescent scattering microscopy is a label-free optical imaging technology that uses evanescent fields and interferometric light scattering to detect and characterize single biomolecules in real time ...

Multicolor EM image of a fungus-infected fly. The nuclei (green) and mitochondria (purple) of the fungus are visible along with the surface structures (SEM) of the fungus-infected fly. This work was ...