2022年5月10日,国际期刊(Vaccines)在线发表中国农业科学院哈尔滨兽医研究所猪病综合防控创新团队和猪蓝耳病与伪狂犬病研究创新团队关于L1分支PRRSV减毒候选疫苗株对我国不同类NADC30 PRRSV交叉保护效果的研究论文,该论文首次报道了L1分支PRRSV候选疫苗株的 ...
PRRSV感染通过调控巨噬细胞CD40表达影响免疫反应,发现病毒N蛋白通过ATF-2增强CD40,而非结构蛋白Nsp1α/Nsp11/Nsp12通过AP-1抑制CD40 ...
推荐 为应对猪繁殖与呼吸综合征病毒1型(PRRSV-1)在中国检出率上升及其与宿主免疫逃逸相关的挑战,研究人员对PRRSV-1非结构蛋白4(NSP4)的遗传变异进行了系统分析。研究发现,中国PRRSV-1 NSP4与全球Subtype I毒株高度相似,但与PRRSV-2存在显著差异,且在83位 ...
篇名:纳米颗粒疫苗触发IFN-γ的产生并赋予对PRRSV的保护性免疫 作者:孙杨杨¹,²,高雁怩¹,²,苏潼键¹,²,张路捷¹,²,周昊然¹,²,张杰¹,²,孙海凤¹,²,白娟¹,²,³,姜平¹,²,³* 作者单位:1.农业部动物疫病诊断与免疫重点实验室;2.教育部动物健康与食品 ...
中国农大新闻网讯 7月12日,中国农业大学动物医学院猪病研究创新团队,在《美国科学院院报》(PNAS)在线发表题为《PRRSV重编程应激颗粒逃逸PKR限制》(Viral evasion of PKR restriction by reprogramming cellular stress granules)的研究论文, 报道了猪繁殖与呼吸征病毒(PRRSV ...
A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV) is due to the response of T cells against the disease, rather than the ...
Tsukuba, Japan—While traditional drug discovery often relies on static crystal structures, many biologically important proteins, including the scavenger receptor CD163-SRCR5, contain flexible loop ...
A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV) is due to the response of T cells against the disease, rather than the ...
Porcine reproductive and respiratory syndrome virus (PRRSV) is the most widespread disease in the swine industry. In sows, PRRSV causes reproductive problems during gestation, including abnormal ...