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The formation of myeloid cells is organized by a hierarchical order of self-renewing pluripotent stem cells and transient lineage-affiliated progenitor-cell stages. Myeloid differentiation fate is ...

Aberrant DNA methylation patterns are a characteristic feature of cancer including myeloid malignancies such as acute myeloid leukemia (AML). The mechanisms behind aberrant DNA methylation have long ...

This study demonstrates that NGS-MSI is noninferior to IHC-MMR and can identify MSI-H tumors that IHC-MMR is unable to detect and conversely IHC-MMR can identify MMRd tumors that NGS-MSI misses. This ...